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A new paradigm for depression in new mothers: the central role of inflammation and how breastfeeding and anti-inflammatory treatments protect maternal mental health

Kathleen Kendall-Tackett email

International Breastfeeding Journal 2007, 2:6doi:10.1186/1746-4358-2-6

Would this be possible?

Nikki Lee   (07 July 2007)  Maternal, Child, and Family Health email

Would it be possible then, to treat some forms of depression with an anti-inflammatory drug, such as ibuprofen?

Competing interests

None declared

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Ibuprofen could be an adjunct treatment

Kathleen Kendall-Tackett   (07 August 2007)  University of New Hampshire email

I wouldn't consider anti-inflammatories, such as ibuprofen, frontline treatments for depression. Nor would recommend trying to treat depression with ibuprofen alone. However, it could be a helpful adjunct. Ibuprofen, like aspirin, lowers risk of cardiovascular disease--most likely because it is anti-inflammatory. Because these same processes are present in depression, anti-inflammatory NSAIDs could potentially help. They also lower pain, which can indirectly lower depression risk.

Competing interests

None.

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